SMOOTH Lab

Southern Medical University | Skin & Mucosal Microbiomics Optimizing Total Health

The SMOOTH Lab investigates the intricate relationships between microbial communities and skin health, developing novel therapies to improve patient outcomes.

50+
Publications
45+
Team Members
20+
Projects
2017+
Since

Research Focus

Skin Microbiome

Characterizing microbial community structures in healthy and diseased skin to identify key biomarkers.

Immune Mechanisms

Investigating how skin bacteria modulate immune cell development and antimicrobial responses.

Therapeutic Translation

Translating microbiome discoveries into novel treatments for skin conditions including acne and wound healing.

Recent Papers

Phytic Acid Improves the Skin Barrier Function in Murine Models of Atopic Dermatitis
2025 Publication

Phytic Acid Improves the Skin Barrier Function in Murine Models of Atopic Dermatitis Through Skin Microbiota-Derived Indole-3-Propionic Acid

Piao Wang, Lan Yang, Lu Chen, Xinyu Huang, Zhen Lin, Yue Li, Caiyu Qi, Tianren Xu, Jianglin Zhang, Min Qi, Biao Cheng, Junjie Wang, Zhiqi Hu, Gaofeng Wang
Allergy, 2025
Published: 2025
Immunotyping the Tumor Microenvironment Reveals Molecular Heterogeneity for Personalized Immunotherapy in Cancer
2025 Publication

Immunotyping the Tumor Microenvironment Reveals Molecular Heterogeneity for Personalized Immunotherapy in Cancer

Dongqiang Zeng, Yunfang Yu, Wenjun Qiu, Qiyun Ou, Qianqian Mao, Luyang Jiang, Jianhua Wu, Jiani Wu, Huiyan Luo, Peng Luo, Wenchao Gu, Na Huang, Siting Zheng, Shaowei Li, Yonghong Lai, Xiatong Huang, Yiran Fang, Qiongzhi Zhao, Rui Zhou, Huiying Sun, Wei Zhang, Jianping Bin, Yulin Liao, Masami Yamamoto, Tetsuya Tsukamoto, Sachiyo Nomura, Min Shi, Wangjun Liao
Advanced Science, 2025, 12(15): e2417593
Published: 2025
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