Our Projects

Current and completed research projects focused on skin & mucosal microbiomics and translational medicine

All Projects
Ongoing
Completed
Funded
Collaborative
Ongoing

Skin Microbiome Biomarkers for Acne Diagnosis and Treatment

πŸ“… 2024 - 2026 πŸ’‘ National Natural Science Foundation of China πŸ’° Grant No.: 82373345
This project aims to identify key microbial biomarkers associated with acne occurrence and severity, and develop microbiome-based diagnostic tools and targeted therapeutic strategies. By analyzing the skin microbiome of acne patients and healthy individuals, we will clarify the role of microbial dysbiosis in acne pathogenesis.
Lead Investigator: Professor Zhang Wei | Team Members: Dr. Li Ming, Dr. Wang Yan, Zhao Hong
Ongoing

Immune Modulation of Skin Microbiome in Atopic Dermatitis

πŸ“… 2023 - 2025 πŸ’‘ Guangdong Provincial Natural Science Foundation πŸ’° Grant No.: 2023A1515012345
This project focuses on the interaction between the skin microbiome and the immune system in atopic dermatitis (AD). We will explore how skin commensal bacteria regulate the development and function of immune cells, and identify potential therapeutic targets for AD by modulating the skin microbiome.
Lead Investigator: Dr. Li Ming | Team Members: Chen Jun, Liu Xia
Completed

Characterization of Skin Microbiome in Healthy Chinese Adults

πŸ“… 2022 - 2023 πŸ’‘ Southern Medical University Research Fund πŸ’° Grant No.: SMU2022PY001
This project established a baseline database of the skin microbiome in healthy Chinese adults, characterized the diversity and composition of skin microbial communities in different body sites, and analyzed the influence of age, gender, and lifestyle on the skin microbiome. The results provided a foundation for subsequent studies on skin microbiome-related diseases.
Lead Investigator: Professor Zhang Wei | Team Members: All Lab Members
Ongoing (Collaborative)

Translational Research on Microbiome-Based Cosmetics for Skin Health

πŸ“… 2024 - 2027 πŸ’‘ Collaborative with Cosmetics Company 🀝 Partner: Guangzhou Beauty Biotechnology Co., Ltd.
This collaborative project aims to translate microbiome research results into practical applications, developing novel cosmetics based on beneficial skin bacteria. We will screen probiotic strains with skin-protective effects, optimize their formulation, and conduct clinical trials to verify their efficacy in improving skin barrier function and reducing skin sensitivity.
Lead Investigator: Dr. Wang Yan | Collaborators: Industry R&D Team, SMOOTH Lab Members